FLT3 internal tandem duplication in CD34(+)/CD33(-) precursors predicts poor outcome in acute myeloid leukemia

Acute myeloid leukemia (AML) is a clonal disease characterized by heterogeneous involvement of hematopoietic stem cell/progenitor cell populations. Using FLT3 internal tandem duplication (FLT3/ITD) as a molecular marker, we tested the hypothesis that clinical outcome in AML correlates with disease i...

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Detalhes bibliográficos
Main Authors: Pollard, Jessica A., Alonzo, Todd A., Gerbing, Robert B., Woods, William G., Lange, Beverly J., Sweetser, David A., Radich, Jerald P., Bernstein, Irwin D., Meshinchi, Soheil
Formato: Artigo
Idioma:Inglês
Publicado em: © 2006 by The American Society of Hematology 2006
Assuntos:
Neoplasia
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC1895585/
https://ncbi.nlm.nih.gov/pubmed/16809615
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1182/blood-2006-04-012260
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