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Development of a macrophage-based nanoparticle platform for antiretroviral drug delivery

Complex dosing regimens, costs, side effects, biodistribution limitations, and variable drug pharmacokinetic patterns have affected the long-term efficacy of antiretroviral medicines. To address these problems, a nanoparticle indinavir (NP-IDV) formulation packaged into carrier bone marrow-derived m...

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Autors principals: Dou, Huanyu, Destache, Christopher J., Morehead, Justin R., Mosley, R. Lee, Boska, Michael D., Kingsley, Jeffrey, Gorantla, Santhi, Poluektova, Larisa, Nelson, Jay A., Chaubal, Mahesh, Werling, Jane, Kipp, James, Rabinow, Barrett E., Gendelman, Howard E.
Format: Artigo
Idioma:Inglês
Publicat: © 2006 by The American Society of Hematology 2006
Matèries:
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC1895582/
https://ncbi.nlm.nih.gov/pubmed/16809617
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1182/blood-2006-03-012534
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