Development of a macrophage-based nanoparticle platform for antiretroviral drug delivery

Complex dosing regimens, costs, side effects, biodistribution limitations, and variable drug pharmacokinetic patterns have affected the long-term efficacy of antiretroviral medicines. To address these problems, a nanoparticle indinavir (NP-IDV) formulation packaged into carrier bone marrow-derived m...

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Detalhes bibliográficos
Main Authors: Dou, Huanyu, Destache, Christopher J., Morehead, Justin R., Mosley, R. Lee, Boska, Michael D., Kingsley, Jeffrey, Gorantla, Santhi, Poluektova, Larisa, Nelson, Jay A., Chaubal, Mahesh, Werling, Jane, Kipp, James, Rabinow, Barrett E., Gendelman, Howard E.
Formato: Artigo
Idioma:Inglês
Publicado em: © 2006 by The American Society of Hematology 2006
Assuntos:
Phagocytes
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC1895582/
https://ncbi.nlm.nih.gov/pubmed/16809617
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1182/blood-2006-03-012534
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