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Oncogenic NRAS rapidly and efficiently induces CMML- and AML-like diseases in mice
Activating mutations in RAS, predominantly NRAS, are common in myeloid malignancies. Previous studies in animal models have shown that oncogenic NRAS is unable to induce myeloid malignancies effectively, and it was suggested that oncogenic NRAS might only act as a secondary mutation in leukemogenesi...
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| Autors principals: | , , |
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| Format: | Artigo |
| Idioma: | Inglês |
| Publicat: |
The American Society of Hematology
2006
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| Matèries: | |
| Accés en línia: | https://ncbi.nlm.nih.gov/pmc/articles/PMC1895567/ https://ncbi.nlm.nih.gov/pubmed/16763213 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1182/blood-2004-08-009498 |
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