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CCAAT/enhancer binding proteins alpha and epsilon cooperate with all-trans retinoic acid in therapy but differ in their antileukemic activities

CCAAT/enhancer binding proteins (C/EBPs) play critical roles in myelopoiesis. Dysregulation of these proteins likely contributes to the pathogenesis of myeloid disorders characterized by a block in granulopoiesis. In one such disease, acute promyelocytic leukemia (APL), a promyelocytic leukemia–reti...

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Detalhes bibliográficos
Main Authors: Lee, Young-Jin, Jones, Letetia C., Timchenko, Nikolai A., Perrotti, Danilo, Tenen, Daniel G., Kogan, Scott C.
Formato: Artigo
Idioma:Inglês
Publicado em: The American Society of Hematology 2006
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC1895555/
https://ncbi.nlm.nih.gov/pubmed/16788101
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1182/blood-2006-02-003582
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