Activation-independent platelet adhesion and aggregation under elevated shear stress

Platelet aggregation, which contributes to bleeding arrest and also to thrombovascular disorders, is thought to initiate after signaling-induced activation. We found that this paradigm does not apply under blood flow conditions comparable to those existing in stenotic coronary arteries. Platelets in...

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Bibliographic Details
Main Authors: Ruggeri, Zaverio M., Orje, Jennifer N., Habermann, Rolf, Federici, Augusto B., Reininger, Armin J.
Format: Artigo
Language:Inglês
Published: The American Society of Hematology 2006
Subjects:
Hemostasis, Thrombosis, and Vascular Biology
Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC1895550/
https://ncbi.nlm.nih.gov/pubmed/16772609
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1182/blood-2006-04-011551
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