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Interleukin-6 induces hepcidin expression through STAT3

Iron homeostasis is maintained through meticulous regulation of circulating hepcidin levels. Hepcidin levels that are inappropriately low or high result in iron overload or iron deficiency, respectively. Although hypoxia, erythroid demand, iron, and inflammation are all known to influence hepcidin e...

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Detalhes bibliográficos
Main Authors: Wrighting, Diedra M., Andrews, Nancy C.
Formato: Artigo
Idioma:Inglês
Publicado em: The American Society of Hematology 2006
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC1895528/
https://ncbi.nlm.nih.gov/pubmed/16835372
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1182/blood-2006-06-027631
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