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G-protein–gated inwardly rectifying potassium channels regulate ADP-induced cPLA(2) activity in platelets through Src family kinases

ADP-induced TXA(2) generation requires the costimulation of P2Y(1), P2Y(12), and the GPIIb/IIIa receptors. Signaling events downstream of the P2Y receptors that contribute to ADP-induced TXA(2) generation have not been clearly delineated. In this study, we have investigated the role of G-protein–gat...

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Détails bibliographiques
Auteurs principaux: Shankar, Haripriya, Kahner, Bryan N., Prabhakar, Janani, Lakhani, Parth, Kim, Soochong, Kunapuli, Satya P.
Format: Artigo
Langue:Inglês
Publié: The American Society of Hematology 2006
Sujets:
Accès en ligne:https://ncbi.nlm.nih.gov/pmc/articles/PMC1895524/
https://ncbi.nlm.nih.gov/pubmed/16857990
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1182/blood-2006-03-010330
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