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STAT3 positively regulates an early step in B-cell development

Transcription factors are critical for instructing the development of B lymphocytes from multipotential progenitor cells in the bone marrow (BM). Here, we show that the absence of STAT3 impaired B-cell development. Mice selectively lacking STAT3 in BM progenitor cells displayed reduced numbers of ma...

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Bibliografske podrobnosti
Main Authors: Chou, Wei-Chun, Levy, David E., Lee, Chien-Kuo
Format: Artigo
Jezik:Inglês
Izdano: The American Society of Hematology 2006
Teme:
Online dostop:https://ncbi.nlm.nih.gov/pmc/articles/PMC1895520/
https://ncbi.nlm.nih.gov/pubmed/16825489
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1182/blood-2006-05-024430
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