Stat1 and Stat2 but Not Stat3 Arbitrate Contradictory Growth Signals Elicited by Alpha/Beta Interferon in T Lymphocytes

Alpha/beta interferon (IFN-α/β) triggers antiviral and antiproliferative responses in target cells through modulation of gene expression. The JAK-STAT pathway is the major mediator of these biological effects through the activation of the transcription factors STAT1 and STAT2, and gene ablation stud...

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Hlavní autoři: Gimeno, Ramon, Lee, Chien-Kuo, Schindler, Christian, Levy, David E.
Médium: Artigo
Jazyk:Inglês
Vydáno: American Society for Microbiology 2005
Témata:
Signal Transduction
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC1156979/
https://ncbi.nlm.nih.gov/pubmed/15964802
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/MCB.25.13.5456-5465.2005
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