B1, a novel HDAC inhibitor, induces apoptosis through the regulation of STAT3 and NF-κB

We previously demonstrated that B1 induced significant cytotoxic effects, cell cycle G1 arrest and apoptosis in human lung cancer A549 cells through the inhibition of DNA topoisomerase II activity. In the present study, we focused on the histone deacetylase (HDAC) modulation of B1 in A549 cells. HDA...

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Publicado no:Int J Mol Med
Main Authors: Cheng, Meng-Hsuan, Wong, Yun-Hong, Chang, Chia-Ming, Yang, Chun-Chien, Chen, Shih-Hua, Yuan, Chun-Lung, Kuo, Hsiao-Mei, Yang, Chun-Yuh, Chiu, Hui-Fen
Formato: Artigo
Idioma:Inglês
Publicado em: D.A. Spandidos 2017
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Articles
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC5403210/
https://ncbi.nlm.nih.gov/pubmed/28393178
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3892/ijmm.2017.2946
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