Enhanced VWF biosynthesis and elevated plasma VWF due to a natural variant in the murine Vwf gene

Both genetic and environmental influences contribute to the wide variation in plasma von Willebrand factor (VWF) levels observed in humans. Inbred mouse strains also have highly variable plasma VWF levels, providing a convenient model in which to study genetic modifiers of VWF. Previously, we identi...

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Main Authors: Lemmerhirt, Heidi L., Shavit, Jordan A., Levy, Gallia G., Cole, Suzanne M., Long, Jeffrey C., Ginsburg, David
Formato: Artigo
Idioma:Inglês
Publicado: The American Society of Hematology 2006
Assuntos:
Hemostasis, Thrombosis, and Vascular Biology
Acceso en liña:https://ncbi.nlm.nih.gov/pmc/articles/PMC1895519/
https://ncbi.nlm.nih.gov/pubmed/16873672
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1182/blood-2006-04-014688
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