Ikaros is required for plasmacytoid dendritic cell differentiation

Plasmacytoid dendritic cells (pDCs) are specialized DCs that produce high levels of type I IFN upon viral infection. Despite their key immunoregulatory role, little is known about pDC ontogeny or how developmental events regulate their function. We show that mice expressing low levels of the transcr...

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Detalhes bibliográficos
Main Authors: Allman, David, Dalod, Marc, Asselin-Paturel, Carine, Delale, Thomas, Robbins, Scott H., Trinchieri, Giorgio, Biron, Christine A., Kastner, Philippe, Chan, Susan
Formato: Artigo
Idioma:Inglês
Publicado em: The American Society of Hematology 2006
Assuntos:
Hematopoiesis
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC1895449/
https://ncbi.nlm.nih.gov/pubmed/16912230
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1182/blood-2006-03-007757
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