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Ikaros is required for plasmacytoid dendritic cell differentiation
Plasmacytoid dendritic cells (pDCs) are specialized DCs that produce high levels of type I IFN upon viral infection. Despite their key immunoregulatory role, little is known about pDC ontogeny or how developmental events regulate their function. We show that mice expressing low levels of the transcr...
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| Asıl Yazarlar: | , , , , , , , , |
|---|---|
| Materyal Türü: | Artigo |
| Dil: | Inglês |
| Baskı/Yayın Bilgisi: |
The American Society of Hematology
2006
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| Konular: | |
| Online Erişim: | https://ncbi.nlm.nih.gov/pmc/articles/PMC1895449/ https://ncbi.nlm.nih.gov/pubmed/16912230 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1182/blood-2006-03-007757 |
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