Ikaros is required for plasmacytoid dendritic cell differentiation

Plasmacytoid dendritic cells (pDCs) are specialized DCs that produce high levels of type I IFN upon viral infection. Despite their key immunoregulatory role, little is known about pDC ontogeny or how developmental events regulate their function. We show that mice expressing low levels of the transcr...

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Bibliographische Detailangaben
Hauptverfasser: Allman, David, Dalod, Marc, Asselin-Paturel, Carine, Delale, Thomas, Robbins, Scott H., Trinchieri, Giorgio, Biron, Christine A., Kastner, Philippe, Chan, Susan
Format: Artigo
Sprache:Inglês
Veröffentlicht: The American Society of Hematology 2006
Schlagworte:
Hematopoiesis
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC1895449/
https://ncbi.nlm.nih.gov/pubmed/16912230
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1182/blood-2006-03-007757
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