Ikaros is required for plasmacytoid dendritic cell differentiation

Plasmacytoid dendritic cells (pDCs) are specialized DCs that produce high levels of type I IFN upon viral infection. Despite their key immunoregulatory role, little is known about pDC ontogeny or how developmental events regulate their function. We show that mice expressing low levels of the transcr...

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Hlavní autoři: Allman, David, Dalod, Marc, Asselin-Paturel, Carine, Delale, Thomas, Robbins, Scott H., Trinchieri, Giorgio, Biron, Christine A., Kastner, Philippe, Chan, Susan
Médium: Artigo
Jazyk:Inglês
Vydáno: The American Society of Hematology 2006
Témata:
Hematopoiesis
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC1895449/
https://ncbi.nlm.nih.gov/pubmed/16912230
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1182/blood-2006-03-007757
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