Selective leukemic-cell killing by a novel functional class of thalidomide analogs

Using a novel cell-based assay to profile transcriptional pathway targeting, we have identified a new functional class of thalidomide analogs with distinct and selective antileukemic activity. These agents activate nuclear factor of activated T cells (NFAT) transcriptional pathways while simultaneou...

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Hlavní autoři: Ge, Yun, Montano, Idalia, Rustici, Gabriella, Freebern, Wendy J., Haggerty, Cynthia M., Cui, Wenwu, Ponciano-Jackson, Damaris, Chandramouli, G. V. R., Gardner, Erin R., Figg, William D., Abu-Asab, Mones, Tsokos, Maria, Jackson, Sharon H., Gardner, Kevin
Médium: Artigo
Jazyk:Inglês
Vydáno: The American Society of Hematology 2006
Témata:
Neoplasia
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC1895447/
https://ncbi.nlm.nih.gov/pubmed/16940421
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1182/blood-2006-04-017046
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