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Selective leukemic-cell killing by a novel functional class of thalidomide analogs
Using a novel cell-based assay to profile transcriptional pathway targeting, we have identified a new functional class of thalidomide analogs with distinct and selective antileukemic activity. These agents activate nuclear factor of activated T cells (NFAT) transcriptional pathways while simultaneou...
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| Main Authors: | , , , , , , , , , , , , , |
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| Format: | Artigo |
| Sprog: | Inglês |
| Udgivet: |
The American Society of Hematology
2006
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| Fag: | |
| Online adgang: | https://ncbi.nlm.nih.gov/pmc/articles/PMC1895447/ https://ncbi.nlm.nih.gov/pubmed/16940421 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1182/blood-2006-04-017046 |
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