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Nitric oxide and cGMP protein kinase (cGK) regulate dendritic-cell migration toward the lymph-node–directing chemokine CCL19
Dendritic-cell (DC) migration to secondary lymphoid organs is crucial for the initiation of adaptive immune responses. Although LPS up-regulates CCR7 on DCs, a second signal is required to enable them to migrate toward the chemokine CCL19 (MIP-3β). We found that the nitric oxide (NO) donor NOR4 prov...
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| Main Authors: | , , |
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| Formato: | Artigo |
| Idioma: | Inglês |
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© 2006 by The American Society of Hematology
2006
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC1895400/ https://ncbi.nlm.nih.gov/pubmed/16249377 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1182/blood-2005-07-2901 |
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