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Differential regulation of endothelial exocytosis of P-selectin and von Willebrand factor by protease-activated receptors and cAMP
Thrombin-mediated endothelial-cell release of von Willebrand factor (VWF) and P-selectin functionally links protease-activated receptors (PARs) to thrombosis and inflammation. VWF release can be stimulated by both Ca(2+) and cAMP, and, although both VWF and P-selectin are found in Weibel-Palade bodi...
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| Main Authors: | , , , |
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| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
The American Society of Hematology
2006
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC1895372/ https://ncbi.nlm.nih.gov/pubmed/16332977 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1182/blood-2004-07-2698 |
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