Total body irradiation selectively induces murine hematopoietic stem cell senescence

Exposure to ionizing radiation (IR) and certain chemotherapeutic agents not only causes acute bone marrow (BM) suppression but also leads to long-term residual hematopoietic injury. This latter effect has been attributed to damage to hematopoietic stem cell (HSC) self-renewal. Using a mouse model, w...

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Bibliografiset tiedot
Päätekijät: Wang, Yong, Schulte, Bradley A., LaRue, Amanda C., Ogawa, Makio, Zhou, Daohong
Aineistotyyppi: Artigo
Kieli:Inglês
Julkaistu: © 2006 by The American Society of Hematology 2006
Aiheet:
Stem Cells in Hematology
Linkit:https://ncbi.nlm.nih.gov/pmc/articles/PMC1895367/
https://ncbi.nlm.nih.gov/pubmed/16150936
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1182/blood-2005-04-1418
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