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Amelioration of a Mouse Model of Osteogenesis Imperfecta with Hematopoietic Stem Cell Transplantation: Micro-Computed Tomography Studies

OBJECTIVE: To test the hypothesis that hematopoietic stem cells (HSCs) generate bone cells using bone marrow (BM) cell transplantation in a mouse model of osteogenesis imperfecta (OI). OI is a genetic disorder resulting from abnormal amount and/or structure of Type I collagen and is characterized by...

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Main Authors: Mehrotra, Meenal, Rosol, Michael, Ogawa, Makio, LaRue, Amanda C.
格式: Artigo
語言:Inglês
出版: 2010
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在線閱讀:https://ncbi.nlm.nih.gov/pmc/articles/PMC2896305/
https://ncbi.nlm.nih.gov/pubmed/20417683
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.exphem.2010.04.008
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