Proangiogenic stimulation of bone marrow endothelium engages mTOR and is inhibited by simultaneous blockade of mTOR and NF-κB

Most bone marrow (BM) malignancies develop in association with an angiogenic phenotype and increased numbers of endothelial cells. The molecular mechanisms involved in the modulation and recruitment of BM endothelium are largely unknown and may provide novel therapeutic targets for neoplastic diseas...

Täydet tiedot

Tallennettuna:
Bibliografiset tiedot
Päätekijät: Costa, Lara F., Balcells, Mercedes, Edelman, Elazer R., Nadler, Lee M., Cardoso, Angelo A.
Aineistotyyppi: Artigo
Kieli:Inglês
Julkaistu: © 2006 by The American Society of Hematology 2006
Aiheet:
Neoplasia
Linkit:https://ncbi.nlm.nih.gov/pmc/articles/PMC1895363/
https://ncbi.nlm.nih.gov/pubmed/16141350
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1182/blood-2005-06-2208
Tagit: Lisää tagi
Ei tageja, Lisää ensimmäinen tagi!

Samankaltaisia teoksia