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Early block to erythromegakaryocytic development conferred by loss of transcription factor GATA-1
Transcription factor GATA-1 is essential at multiple stages of hematopoiesis. Murine gene targeting and analysis of naturally occurring human mutations demonstrate that GATA-1 drives the maturation of committed erythroid precursors and megakaryocytes. Prior studies also suggest additional, poorly de...
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| Главные авторы: | , , |
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| Формат: | Artigo |
| Язык: | Inglês |
| Опубликовано: |
© 2006 by The American Society of Hematology
2006
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| Предметы: | |
| Online-ссылка: | https://ncbi.nlm.nih.gov/pmc/articles/PMC1895362/ https://ncbi.nlm.nih.gov/pubmed/16144799 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1182/blood-2005-07-2740 |
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