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Ligand-induced internalization selects use of common receptor neuropilin-1 by VEGF(165) and semaphorin3A

Neuropilin-1 (Npn-1) is a receptor shared by class 3 semaphorins and heparin-binding forms of vascular endothelial growth factor (VEGF), protein families that regulate endothelial and neuronal-cell function. Ligand interaction with Npn-1 dictates the choice of signal transducer; plexins transduce se...

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Autori principali: Narazaki, Masashi, Tosato, Giovanna
Natura: Artigo
Lingua:Inglês
Pubblicazione: The American Society of Hematology 2006
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Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC1895286/
https://ncbi.nlm.nih.gov/pubmed/16424390
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1182/blood-2005-10-4113
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