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Glycoprotein VI–dependent and –independent pathways of thrombus formation in vivo

The role of the collagen receptor glycoprotein VI (GPVI) in arteriolar thrombus formation was studied in FcRγ-null mice (FcRγ(–/–)) lacking platelet surface GPVI. Thrombi were induced with severe or mild FeCl(3) injury. Collagen exposure was significantly delayed and diminished in mild compared with...

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Autors principals: Dubois, Christophe, Panicot-Dubois, Laurence, Merrill-Skoloff, Glenn, Furie, Bruce, Furie, Barbara C.
Format: Artigo
Idioma:Inglês
Publicat: The American Society of Hematology 2006
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Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC1895285/
https://ncbi.nlm.nih.gov/pubmed/16455953
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1182/blood-2005-09-3687
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