Inducible activation of CEBPB, a gene negatively regulated by BCR/ABL, inhibits proliferation and promotes differentiation of BCR/ABL-expressing cells

Translational regulation by oncogenic proteins may be a rapid and efficient mechanism to modulate gene expression. We report here the identification of the CEBPB gene as a target of translational regulation in myeloid precursor cells transformed by the BCR/ABL oncogene. Expression of CEBPB was repre...

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Bibliographische Detailangaben
Hauptverfasser: Guerzoni, Clara, Bardini, Michela, Mariani, Samanta A., Ferrari-Amorotti, Giovanna, Neviani, Paolo, Panno, Maria Luisa, Zhang, Ying, Martinez, Robert, Perrotti, Danilo, Calabretta, Bruno
Format: Artigo
Sprache:Inglês
Veröffentlicht: The American Society of Hematology 2006
Schlagworte:
Neoplasia
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC1895282/
https://ncbi.nlm.nih.gov/pubmed/16418324
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1182/blood-2005-08-3181
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