Dectin-1 activates Syk tyrosine kinase in a dynamic subset of macrophages for reactive oxygen production

Dectin-1 is a lectin receptor for β-glucan that is important for innate macrophage recognition of fungi and contributes to phagocytosis, reactive oxygen production, and induction of inflammatory cytokines. The mechanisms by which Dectin-1 mediates intracellular signaling are just beginning to be def...

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Bibliographic Details
Main Authors: Underhill, David M., Rossnagle, Eddie, Lowell, Clifford A., Simmons, Randi M.
Format: Artigo
Language:Inglês
Published: The American Society of Hematology 2005
Subjects:
Phagocytes
Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC1895265/
https://ncbi.nlm.nih.gov/pubmed/15956283
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1182/blood-2005-03-1239
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