HIV-1 Nef-induced FasL induction and bystander killing requires p38 MAPK activation

The human immunodeficiency virus (HIV) has been reported to target noninfected CD4 and CD8 cells for destruction. This effect is manifested in part through up-regulation of the death receptor Fas ligand (FasL) by HIV-1 negative factor (Nef), leading to bystander damage. However, the signal transduct...

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Bibliografiska uppgifter
Huvudupphovsmän: Muthumani, Karuppiah, Choo, Andrew Y., Hwang, Daniel S., Premkumar, Arumugam, Dayes, Nathanael S., Harris, Crafford, Green, Douglas R., Wadsworth, Scott A., Siekierka, John J., Weiner, David B.
Materialtyp: Artigo
Språk:Inglês
Publicerad: The American Society of Hematology 2005
Ämnen:
Immunobiology
Länkar:https://ncbi.nlm.nih.gov/pmc/articles/PMC1895138/
https://ncbi.nlm.nih.gov/pubmed/15928037
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1182/blood-2005-03-0932
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