Heat shock protein 90 inhibition sensitizes acute myelogenous leukemia cells to cytarabine

Previous studies demonstrated that ataxia telangiectasia mutated– and Rad3-related (ATR) kinase and its downstream target checkpoint kinase 1 (Chk1) facilitate survival of cells treated with nucleoside analogs and other replication inhibitors. Recent results also demonstrated that Chk1 is depleted w...

Descrizione completa

Salvato in:
Dettagli Bibliografici
Autori principali: Mesa, Ruben A., Loegering, David, Powell, Heather L., Flatten, Karen, Arlander, Sonnet J. H., Dai, Nga T., Heldebrant, Michael P., Vroman, Benjamin T., Smith, B. Douglas, Karp, Judith E., Ten Eyck, Cynthia J., Erlichman, Charles, Kaufmann, Scott H., Karnitz, Larry M.
Natura: Artigo
Lingua:Inglês
Pubblicazione: © 2005 by The American Society of Hematology 2005
Soggetti:
Neoplasia
Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC1895127/
https://ncbi.nlm.nih.gov/pubmed/15784732
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1182/blood-2004-09-3523
Tags: Aggiungi Tag
Nessun Tag, puoi essere il primo ad aggiungerne! !

Documenti analoghi