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Phorbol ester-induced down modulation of tailless CD4 receptors requires prior binding of gp120 and suggests a role for accessory molecules.

The entry of human immunodeficiency virus type 1 into cells proceeds via a fusion mechanism that is initiated by binding of the viral glycoprotein gp120-gp41 to its cellular receptor CD4. Species- and tissue-specific restrictions to viral entry suggested the participation of additional membrane comp...

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Autors principals: Golding, H, Dimitrov, D S, Manischewitz, J, Broder, C C, Robinson, J, Fabian, S, Littman, D R, Lapham, C K
Format: Artigo
Idioma:Inglês
Publicat: 1995
Matèries:
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC189511/
https://ncbi.nlm.nih.gov/pubmed/7545243
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