Enhancement of human immunodeficiency virus type 1 envelope-mediated fusion by a CD4-gp120 complex-specific monoclonal antibody.

The entry of human immunodeficiency virus type 1 (HIV-1) into cells is initiated by binding of the viral glycoprotein gp120-gp41 to its cellular receptor CD4. The gp120-CD4 complex formed at the cell surface undergoes conformational changes that may allow its association with an additional membrane...

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Detalhes bibliográficos
Main Authors: Lee, S, Peden, K, Dimitrov, D S, Broder, C C, Manischewitz, J, Denisova, G, Gershoni, J M, Golding, H
Formato: Artigo
Idioma:Inglês
Publicado em: 1997
Assuntos:
Research Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC191861/
https://ncbi.nlm.nih.gov/pubmed/9223495
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