p21-activated kinase (Pak) regulates NADPH oxidase activation in human neutrophils

The phagocyte nicotinamide adenine dinucleotide phosphate (NADPH) oxidase plays an instrumental role in host defense and contributes to microbicial killing by releasing highly reactive oxygen species. This multicomponent enzyme is composed of membrane and cytosolic components that assemble in the pl...

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Hlavní autoři: Martyn, Kendra D., Kim, Moon-Ju, Quinn, Mark T., Dinauer, Mary C., Knaus, Ulla G.
Médium: Artigo
Jazyk:Inglês
Vydáno: © 2005 by The American Society of Hematology 2005
Témata:
Phagocytes
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC1895105/
https://ncbi.nlm.nih.gov/pubmed/16099876
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1182/blood-2005-03-0859
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