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Thrombopoietin enhances expression of vascular endothelial growth factor (VEGF) in primitive hematopoietic cells through induction of HIF-1α
Thrombopoietin (TPO), the primary regulator of thrombopoiesis, is also an important, nonredundant mediator of hematopoietic stem cell (HSC) development. For example, following transplantation, HSC expansion is approximately 15-fold more robust in normal than in Tpo(-/-) mice. Vascular endothelial gr...
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| Main Authors: | , , , |
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| Formato: | Artigo |
| Idioma: | Inglês |
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© 2005 by The American Society of Hematology
2005
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| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC1895043/ https://ncbi.nlm.nih.gov/pubmed/15705785 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1182/blood-2004-07-2712 |
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