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Intronic splicing of hyaluronan synthase 1 (HAS1): a biologically relevant indicator of poor outcome in multiple myeloma

In this study, we show that the hyaluronan synthase 1 (HAS1) gene undergoes aberrant intronic splicing in multiple myeloma (MM). In addition to HAS1 full length (HAS1(FL)), we identify 3 novel splice variants of HAS1, HAS1Va, HAS1Vb, and HAS1Vc, detected in patients with MM or monoclonal gammopathy...

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Detalhes bibliográficos
Main Authors: Adamia, Sophia, Reiman, Tony, Crainie, Mary, Mant, Michael J., Belch, Andrew R., Pilarski, Linda M.
Formato: Artigo
Idioma:Inglês
Publicado em: The American Society of Hematology 2005
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Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC1894997/
https://ncbi.nlm.nih.gov/pubmed/15731173
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1182/blood-2004-10-3825
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