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Aberrant Splice Variants of HAS1 (Hyaluronan Synthase 1) Multimerize with and Modulate Normally Spliced HAS1 Protein: A POTENTIAL MECHANISM PROMOTING HUMAN CANCER

Most human genes undergo alternative splicing, but aberrant splice forms are hallmarks of many cancers, usually resulting from mutations initiating abnormal exon skipping, intron retention, or the introduction of a new splice sites. We have identified a family of aberrant splice variants of HAS1 (th...

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מידע ביבליוגרפי
Main Authors: Ghosh, Anirban, Kuppusamy, Hemalatha, Pilarski, Linda M.
פורמט: Artigo
שפה:Inglês
יצא לאור: American Society for Biochemistry and Molecular Biology 2009
נושאים:
גישה מקוונת:https://ncbi.nlm.nih.gov/pmc/articles/PMC2707203/
https://ncbi.nlm.nih.gov/pubmed/19451652
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1074/jbc.M109.013813
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