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Predicting helical coaxial stacking in RNA multibranch loops

The hypothesis that RNA coaxial stacking can be predicted by free energy minimization using nearest-neighbor parameters is tested. The results show 58.2% positive predictive value (PPV) and 65.7% sensitivity for accuracy of the lowest free energy configuration compared with crystal structures. The p...

Deskribapen osoa

Gorde:
Xehetasun bibliografikoak
Egile Nagusiak: Tyagi, Rahul, Mathews, David H.
Formatua: Artigo
Hizkuntza:Inglês
Argitaratua: Cold Spring Harbor Laboratory Press 2007
Gaiak:
Sarrera elektronikoa:https://ncbi.nlm.nih.gov/pmc/articles/PMC1894924/
https://ncbi.nlm.nih.gov/pubmed/17507661
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1261/rna.305307
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