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Fluorescence Competition and Optical Melting Measurements of RNA Three-Way Multibranch Loops Provide a Revised Model for Thermodynamic Parameters

[Image: see text] Three-way multibranch loops (junctions) are common in RNA secondary structures. Computer algorithms such as RNAstructure and MFOLD do not consider the identity of unpaired nucleotides in multibranch loops when predicting secondary structure. There is limited experimental data, howe...

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Detalhes bibliográficos
Main Authors: Liu, Biao, Diamond, Joshua M., Mathews, David H., Turner, Douglas H.
Formato: Artigo
Idioma:Inglês
Publicado em: American Chemical Society 2010
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3032278/
https://ncbi.nlm.nih.gov/pubmed/21133351
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1021/bi101470n
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