Fluorescence Competition and Optical Melting Measurements of RNA Three-Way Multibranch Loops Provide a Revised Model for Thermodynamic Parameters

[Image: see text] Three-way multibranch loops (junctions) are common in RNA secondary structures. Computer algorithms such as RNAstructure and MFOLD do not consider the identity of unpaired nucleotides in multibranch loops when predicting secondary structure. There is limited experimental data, howe...

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Bibliografiske detaljer
Main Authors: Liu, Biao, Diamond, Joshua M., Mathews, David H., Turner, Douglas H.
Format: Artigo
Sprog:Inglês
Udgivet: American Chemical Society 2010
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC3032278/
https://ncbi.nlm.nih.gov/pubmed/21133351
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1021/bi101470n
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