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Predicting helical coaxial stacking in RNA multibranch loops
The hypothesis that RNA coaxial stacking can be predicted by free energy minimization using nearest-neighbor parameters is tested. The results show 58.2% positive predictive value (PPV) and 65.7% sensitivity for accuracy of the lowest free energy configuration compared with crystal structures. The p...
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| Main Authors: | , |
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| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
Cold Spring Harbor Laboratory Press
2007
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| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC1894924/ https://ncbi.nlm.nih.gov/pubmed/17507661 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1261/rna.305307 |
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