Regulatory Polymorphisms in the Cyclophilin A Gene, PPIA, Accelerate Progression to AIDS

Human cyclophilin A, or CypA, encoded by the gene peptidyl prolyl isomerase A (PPIA), is incorporated into the HIV type 1 (HIV-1) virion and promotes HIV-1 infectivity by facilitating virus uncoating. We examined the effect of single nucleotide polymorphisms (SNPs) and haplotypes within the PPIA gen...

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Hlavní autoři: An, Ping, Wang, Li Hua, Hutcheson-Dilks, Holli, Nelson, George, Donfield, Sharyne, Goedert, James J, Rinaldo, Charles R, Buchbinder, Susan, Kirk, Gregory D, O'Brien, Stephen J, Winkler, Cheryl A
Médium: Artigo
Jazyk:Inglês
Vydáno: Public Library of Science 2007
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Research Article
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC1894826/
https://ncbi.nlm.nih.gov/pubmed/17590083
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.ppat.0030088
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