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A comparison of relative abundance, activity factor and inhibitory monoclonal antibody approaches in the characterization of human CYP enzymology

AIMS: The objective of this study was to evaluate the potential uses of relative abundance, relative activity approaches and inhibitory monoclonal antibodies (mAbs) in the characterization of CYP enzymology in early drug discovery. METHODS: Intrinsic clearance estimates for the oxidation of ethoxyre...

Deskribapen osoa

Gorde:
Xehetasun bibliografikoak
Egile Nagusiak: Soars, Matthew G, Gelboin, Harry V, Krausz, Kristopher W, Riley, Robert J
Formatua: Artigo
Hizkuntza:Inglês
Argitaratua: Blackwell Science Inc 2003
Gaiak:
Sarrera elektronikoa:https://ncbi.nlm.nih.gov/pmc/articles/PMC1894739/
https://ncbi.nlm.nih.gov/pubmed/12580989
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1046/j.1365-2125.2003.01721.x
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