A comparison of relative abundance, activity factor and inhibitory monoclonal antibody approaches in the characterization of human CYP enzymology

AIMS: The objective of this study was to evaluate the potential uses of relative abundance, relative activity approaches and inhibitory monoclonal antibodies (mAbs) in the characterization of CYP enzymology in early drug discovery. METHODS: Intrinsic clearance estimates for the oxidation of ethoxyre...

Full description

Saved in:
Bibliographic Details
Main Authors: Soars, Matthew G, Gelboin, Harry V, Krausz, Kristopher W, Riley, Robert J
Format: Artigo
Language:Inglês
Published: Blackwell Science Inc 2003
Subjects:
Drug Disposition
Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC1894739/
https://ncbi.nlm.nih.gov/pubmed/12580989
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1046/j.1365-2125.2003.01721.x
Tags: Add Tag
No Tags, Be the first to tag this record!

Similar Items