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Altered collecting duct adenylyl cyclase content in collecting duct endothelin-1 knockout mice

BACKGROUND: Endothelin-1 (ET-1) inhibition of vasopressin (AVP)-stimulated water reabsorption by the inner medullary collecting duct (IMCD) is associated with reduced cAMP accumulation. To determine the effect of ET-1 deficiency, AVP-stimulated cAMP responsiveness was assessed in IMCD from mice with...

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Autori principali: Strait, Kevin A, Stricklett, Peter K, Kohan, Donald E
Natura: Artigo
Lingua:Inglês
Pubblicazione: BioMed Central 2007
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Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC1894628/
https://ncbi.nlm.nih.gov/pubmed/17521429
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/1471-2369-8-8
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