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Effect of mineralocorticoid treatment in mice with collecting duct-specific knockout of endothelin-1
Aldosterone increases blood pressure (BP) by stimulating sodium (Na) reabsorption within the distal nephron and collecting duct (CD). Aldosterone also stimulates endothelin-1 (ET-1) production that acts within the CD to inhibit Na reabsorption via a negative feedback mechanism. We tested the hypothe...
Enregistré dans:
| Publié dans: | Am J Physiol Renal Physiol |
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| Auteurs principaux: | , , , , , |
| Format: | Artigo |
| Langue: | Inglês |
| Publié: |
American Physiological Society
2015
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| Sujets: | |
| Accès en ligne: | https://ncbi.nlm.nih.gov/pmc/articles/PMC4683304/ https://ncbi.nlm.nih.gov/pubmed/26400543 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1152/ajprenal.00220.2015 |
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