Effect of mineralocorticoid treatment in mice with collecting duct-specific knockout of endothelin-1

Aldosterone increases blood pressure (BP) by stimulating sodium (Na) reabsorption within the distal nephron and collecting duct (CD). Aldosterone also stimulates endothelin-1 (ET-1) production that acts within the CD to inhibit Na reabsorption via a negative feedback mechanism. We tested the hypothe...

Disgrifiad llawn

Wedi'i Gadw mewn:
Manylion Llyfryddiaeth
Cyhoeddwyd yn:Am J Physiol Renal Physiol
Prif Awduron: Lynch, I. Jeanette, Welch, Amanda K., Gumz, Michelle L., Kohan, Donald E., Cain, Brian D., Wingo, Charles S.
Fformat: Artigo
Iaith:Inglês
Cyhoeddwyd: American Physiological Society 2015
Pynciau:
Articles
Mynediad Ar-lein:https://ncbi.nlm.nih.gov/pmc/articles/PMC4683304/
https://ncbi.nlm.nih.gov/pubmed/26400543
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1152/ajprenal.00220.2015
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