Genetic restriction of HIV-1 pathogenesis to AIDS by promoter alleles of IL10

IL10 is a powerful TH-2 cell cytokine produced by lymphoid cells that limits HIV-1 replication in vivo, ostensibly by inhibiting macrophage/monocyte and T-cell lymphocyte replication and secretion of inflammatory cytokines (IL1, TNFα, IL6, IL8, and IL12). A genetic epidemiological scan of patients e...

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Bibliografische gegevens
Hoofdauteurs: Shin, Hyoung Doo, Winkler, Cheryl, Stephens, J. Claiborne, Bream, Jay, Young, Howard, Goedert, James J., O'Brien, Thomas R., Vlahov, David, Buchbinder, Susan, Giorgi, Janis, Rinaldo, Charles, Donfield, Sharyne, Willoughby, Anne, O'Brien, Stephen J., Smith, Michael W.
Formaat: Artigo
Taal:Inglês
Gepubliceerd in: The National Academy of Sciences 2000
Onderwerpen:
Biological Sciences
Online toegang:https://ncbi.nlm.nih.gov/pmc/articles/PMC18942/
https://ncbi.nlm.nih.gov/pubmed/11121048
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