A novel method for efficient amplification of whole hepatitis B virus genomes permits rapid functional analysis and reveals deletion mutants in immunosuppressed patients.
Current knowledge of hepatitis B virus (HBV) sequence heterogeneity is based mainly on sequencing of amplified subgenomic HBV fragments. Here, we describe a method which allows sensitive amplification and simplified functional analysis of full-length HBV genomes with or without prior cloning. By thi...
محفوظ في:
| الحاوية / القاعدة: | J Virol |
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| المؤلفون الرئيسيون: | , , , , , |
| التنسيق: | Artigo |
| اللغة: | Inglês |
| منشور في: |
American Society for Microbiology (ASM)
1995
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| الموضوعات: | |
| الوصول للمادة أونلاين: | https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC189390/ https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/7636989/ https://ncbi.nlm.nih.govhttps://doi.org/10.1128/jvi.69.9.5437-5444.1995 |
| الوسوم: |
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