Diverse Effects of the NTCP p.Ser267Phe Variant on Disease Progression During Chronic HBV Infection and on HBV preS1 Variability

The sodium taurocholate co-transporting polypeptide (NTCP) acts as a cellular receptor for the hepatitis B virus (HBV) infection on host hepatocytes. We aim to investigate how the NTCP p.Ser267Phe variant affects HBV-related disease progression and analyze viral genomic variability under a host gene...

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Bibliografische Detailangaben

Hauptverfasser:	Fangji Yang, Lina Wu, Wenxiong Xu, Ying Liu, Limin Zhen, Gang Ning, Jie Song, Qian Jiao, Yongyuan Zheng, Tongtong Chen, Chan Xie, Liang Peng
Format:	Artigo
Sprache:	Inglês
Veröffentlicht:	Frontiers Media S.A. 2019-03-01
Schriftenreihe:	Frontiers in Cellular and Infection Microbiology
Schlagworte:	sodium taurocholate co-transporting polypeptide (NTCP) hepatitis hepatitis B virus (HBV) preS1 region single nucleotide polymorphism (SNP)
Online-Zugang:	https://www.frontiersin.org/article/10.3389/fcimb.2019.00018/full
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