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The foot-and-mouth disease virus leader proteinase gene is not required for viral replication.

The foot-and-mouth disease virus (FMDV) leader (L) proteinase has only two known functions: (i) autocatalytic removal from the N terminus of the viral polyprotein and (ii) cleavage of the p220 subunit of the eukaryotic initiation factor 4F complex, which helps to shut off host protein synthesis. Cle...

Ausführliche Beschreibung

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Bibliographische Detailangaben
Hauptverfasser: Piccone, M E, Rieder, E, Mason, P W, Grubman, M J
Format: Artigo
Sprache:Inglês
Veröffentlicht: 1995
Schlagworte:
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC189380/
https://ncbi.nlm.nih.gov/pubmed/7636982
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