(-)-2'-deoxy-3'-thiacytidine is a potent, highly selective inhibitor of human immunodeficiency virus type 1 and type 2 replication in vitro.

The (-)-enantiomer of 2'-deoxy-3'-thiacytidine (3TC) was found to be a potent and selective inhibitor of human immunodeficiency virus types 1 (HIV-1) and 2 (HIV-2) in vitro. We determined its antiviral activity against a number of laboratory strains of HIV-1 and HIV-2 in a range of CD4-bearing lymph...

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Detalhes bibliográficos

Publicado no:	Antimicrob Agents Chemother
Principais autores:	Coates, J A, Cammack, N, Jenkinson, H J, Jowett, A J, Jowett, M I, Pearson, B A, Penn, C R, Rouse, P L, Viner, K C, Cameron, J M
Formato:	Artigo
Idioma:	Inglês
Publicado em:	American Society for Microbiology (ASM) 1992
Assuntos:	Research Article
Acesso em linha:	https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC189378/ https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/1380229/ https://ncbi.nlm.nih.govhttps://doi.org/10.1128/aac.36.4.733
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