Construction of intertypic chimeric dengue viruses exhibiting type 3 antigenicity and neurovirulence for mice.

There are four dengue virus serotypes (DEN1 to -4), each of which causes major epidemics in tropical or subtropical areas. The current strategy for dengue virus immunization favors the use of a tetravalent vaccine preparation. We have previously employed full-length DEN4 cDNA to construct a viable i...

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Bibliographic Details
Main Authors: Chen, W, Kawano, H, Men, R, Clark, D, Lai, C J
Format: Artigo
Language:Inglês
Published: 1995
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Research Article
Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC189343/
https://ncbi.nlm.nih.gov/pubmed/7609092
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